Why you need it
Antacid causes magnesium deficiency: Tip of the Iceberg?
Millions or people use antacids daily. some patients develop a serious hypomagnesaemia resulting in muscle cramps, diabetes and even cardiovascular diseases. Anke Lameris, PhD investigated the molecular mechanism responsible for the side effect of drugs like omeprazole. She successfully defended her PhD thesis entitled "Divalent Digestion: Insight in Intestinal lontransport" on Feb 4th 2014 at the Radboud University, in the Netherlands. Lameris investigated the molecular mechanism underlying this deficit and came up with a possible solution to the problem. Magnesium is essential for our body. It plays a role in the contraction of muscles, heart rhythm, the nervous system, glucose balance and allows for strong bones and teeth.
Cause found
The antacid omeprazole has been available for several vears 'over the counter. In the U.S it is in the top ten most commonly used medications. But every vear some users end up in the hospital with cardiac arrhythmias and muscle spasms caused by magnesium deficiency. Lameris researched this and claims that omeprazole inhibits the transport of magnesium through the so called ion channel TRPM6. Lameris presumes that there's also a genetic component involved.
Omeprazole
Omeprazole belongs to the family of medications called proton pump inhibitors (PPI), that slow or prevent the production of acid within the stomach.
It is used for instance to heal gastric and duodenal ulcers. In addition, it is widely used to prevent and treat ulcers, heartburn, and gastroesophageal reflux disease associated with medications known as NSAIDs. The most prominent members in this group of drugs are aspirin, ibuprofen and naproxen, which are all available over the counter in most countries.
Treatment
The results of Laméris’ research can help to develop new treatments for patients with impaired magnesium metabolism caused by omeprazole. Currently, researchers of the Radboud University are testing a group of patients on a dietary supplement.
Magnesium Health Institute comments: Many other medicines cause magnesium deficiency.
Severe deficiency
Currently it is academically proved that a hundred patients have severe magnesium deficiency caused by omeprazole. However, this research has only started recently and given the huge number of users worldwide, this might be the tip of the iceberg. Magnesium deficiency should be detected in its early stages, because a magnesium deficiency plays an important role in the development of disorders such as diabetes and cardio vascular diseases.
The right product?
Zechstein magnesium products are available at the majoritv of drugstores, both in-store and online.
When purchasing in store, note the Lechstein inside logo. This gives the guarantee that it concerns the pure and natural products from the Zechstein source. If you buy online and do not see the Zechstein logo inside make sure that the Zechstein source is mentioned in the product description.